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4.7/5 based on over 700 ratings

Sereniser

The Sereniser is your hormone-free solution that supports relaxation and restful sleep.* The Sereniser consists of a groundbreaking blend of synergistic ingredients, including Safr'Inside™ (saffron extract), Holixer™ (basil extract), Serezin™ (ginger and frankincense extract), L-theanine, magnesium bisglycinate, and vitamin B6 ensuring that you wake up full of energy every morning.**

* Saffron promotes relaxation and better sleep.

** Magnesium and vitamin B6 contribute to normal energy metabolism and the reduction of fatigue.

Support your sleep naturally.

Many sleep aids rely on melatonin or sedatives to artificially induce sleep. The Sereniser, on the other hand, was deliberately developed to support your body's natural sleep-wake rhythm.

The Sereniser was developed in collaboration with longevity researchers from Switzerland. It follows a multidimensional approach based on findings from neuroscience and chronobiology.

Supports relaxation Promotes recovery

The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional medicine and modern science. Saffron contributes to relaxation and better sleep.

The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional medicine and modern science. Saffron contributes to relaxation and better sleep.

Vitamin B6 and magnesium help the body recover and reduce tiredness and fatigue.

Support your sleep naturally.
  • Supports relaxation
    The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional medicine and modern science. Saffron contributes to relaxation and better sleep.
  • Promotes recovery
    Vitamin B6 and magnesium help the body recover and reduce tiredness and fatigue.
  • Non-habit forming
    In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support your body's sleep-wake rhythm.
  • Best quality and purity
    We only use ingredients from leading raw material producers with the highest bioavailability. All products are tested for purity in an independent laboratory in Switzerland.
Non-habit forming Best quality and purity

In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support your body's sleep-wake rhythm.

In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support your body's sleep-wake rhythm.

We only use ingredients from leading raw material producers with the highest bioavailability. All products are tested for purity in an independent laboratory in Switzerland.

Supports relaxation

The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional medicine and modern science. Saffron contributes to relaxation and better sleep.

Promotes recovery

Vitamin B6 and magnesium help the body recover and reduce tiredness and fatigue.

Non-habit forming

In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support your body's sleep-wake rhythm.

Best quality and purity

We only use ingredients from leading raw material producers with the highest bioavailability. All products are tested for purity in an independent laboratory in Switzerland.

Sleep science 101

The science behind deep, restorative sleep

Sleep is not just about duration – it’s about depth, cycles, and consistency.

Most of us know we need 7–9 hours of sleep, but not all sleep is created equal.

Throughout the night, your brain moves through a series of stages—light sleep, deep sleep (also known as slow-wave sleep), and REM sleep (when most dreaming occurs).  These stages cycle roughly every 90 minutes and each plays a distinct role in how your body and mind recover.

  • Light sleep helps the body relax and stabilise, preparing for deeper, restorative sleep stages.
  • Deep sleep is when the body repairs muscle, restores energy, and strengthens the immune system.
  • REM sleep supports memory consolidation, emotional processing, and cognitive performance.

But as we age, our sleep architecture begins to shift.

Older adults tend to spend more time in lighter stages and less in slow-wave and REM sleep. The amount of deep sleep for mature adults declines steadily – making sleep more fragmented and less restorative, even if you’re getting enough hours.

At the same time, the circadian rhythm, your body’s internal clock, becomes less stable. Many people experience a shift known as phase advance, feeling sleepy earlier in the evening and waking earlier in the morning, often before they’ve had adequate rest. Hormonal shifts, especially for women during perimenopause and menopause, also contribute to this disruption. 

These changes don’t just impact how rested you feel – they affect your long-term health.

Deep, uninterrupted sleep is strongly linked to healthy ageing and longevity. It influences immune resilience, hormone balance, metabolic function, and even how efficiently the brain clears out waste through the glymphatic system.

When sleep becomes shallow or inconsistent, the body’s ability to repair, regulate, and renew itself also begins to decline.

Feel the dıfference

Many users describe feeling more balanced and at ease with Sereniser.*

93%

report an increase in general well-being*

wake up more refreshed in the morning*

37%

experienced more serenity after 8 weeks**

4 weeks

After just 4 weeks, many felt noticeably less exhausted***
* PLT Health, 2023 (Serezin™ Clinical Study) ** Frontiers in Nutrition, 2022 (Holixer™ clinical study) *** Lang et al., medRxiv, 2025 (Safr'Inside™ clinical study)

Saffron promotes relaxation and better sleep. Saffron contributes to emotional balance and a positive mood. Magnesium and vitamin B6 contribute to normal energy metabolism and the reduction of fatigue.

Sereniser

Restful Sleep
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Discover the science behind the Sereniser

Developed by leading scientists in Switzerland, the Sereniser combines valuable plant extracts such as Safr’Inside™, Holixer™ and Serezin™ with L-theanine, magnesium bisglycinate and vitamin B6.

Third-party test results

Safr’Inside™

30 mg

A patented, standardized, and highly bioavailable saffron extract. Saffron has been used for centuries in Chinese, Indian, and European medicine.

Holixer™

250 mg

A clinically tested extract from holy basil (also known as Indian basil). Holy basil is widely used in traditional Ayurvedic medicine.

Serezin™

300 mg

An innovative combination of natural Ginger and frankincense extracts. Frankincense contains various essential oils, polysaccharides and terpenes which are said to have positive effects in traditional medicine.

L-Theanine

200 mg

A naturally occurring amino acid from green tea that is responsible for the calm, focused state experienced after drinking green tea.

Magnesium Bisglycinate

56.25 mg

Magnesium also occurs naturally in foods like sunflower seeds. We use a particularly bioavailable form: magnesium bisglycinate. By binding to glycine, a soothing amino acid, it is particularly gentle on the stomach and effective.

Vitamin B6

1.4 mg

An essential cofactor in the formation of GABA and serotonin – two key neurotransmitters that regulate mood and sleep. Naturally found in seeds and nuts, it supports Vitamin B6 a balanced day-night rhythm and strengthens the body's resistance to stress.

Third-party test results

Frequently asked questions